It might be difficult to do business in San Francisco, but it's certainly easy to undo a business.
All you need to do is say that a park or an Alcoholics Anonymous meeting hall is the same thing as a school, and you can keep a business closed for, say, seven months while its operator shells out money for rent with no income.
That may be enough to put the business out of business before it ever was in business. And here's the kicker: You don't even need to live in San Francisco to do it.
Just ask onetime supervisor candidate Leon Chow, who made political hay in the Excelsior District earlier this year when he employed this strategy to oppose businesses, specifically marijuana business.